EXTRO-Lab
EXTRO-Lab

NEWS

December 2022

 

FWF (Austrian Science Fund) Project P36528-B "Radiation-induced and obesity dependent NK cell activities against metastatic breast cancer cells" has been approved and funded.

 

The project starts in March 2023 and a PhD Student position is open. Please send your applications to Ira.Skvortsova(at)i-med.ac.at

 

May 2021

 

Article by Bertram Aschenbrenner is published:

 

Aschenbrenner B, Negro G, Savic D, Sorokin M, Buzdin A, Ganswindt U, Cemazar M, Sersa G, Skvortsov S, Skvortsova I.

Simvastatin is effective in killing the radioresistant breast carcinoma cells.

Radiol Oncol. 2021 May 4;55(3):305-316. doi: 10.2478/raon-2021-0020.PMID: 33939900

 

April 22, 2021

Nanolive Live Cell Imaging Regional Seminar (Austria), April 22,2021

 

March 2021

Submit your manuscripts to the journal "Advances in Cancer Biology - Metastasis" (Editor-in-Chief: Ira Skvortsova)

 

25.03.2020

 

Dear Colleagues,

 

Cancer stem cells (CSCs) are considered the root of primary and acquired therapy resistances associated with disease progression and poor clinical outcomes in cancer patients. Therefore, an elucidation of the key molecular mechanisms regulating CSC activities could help with the development of novel biomarkers and therapeutic targets to predict or combat the most aggressive malignant tumors in patients.

 

The following aspects of the subject area will be highlighted in this Special Issue:


- signalling pathways;

- CSCs in treatment failure;

- CSC metabolism;

- circadian rhythms in CSCs;

- CSCs and microenvironmental factors;

- biological, biochemical, and pathological methods allowing CSC identification within malignant tumors;

- pediatric tumors and CSCs;

- epigenetic factors in CSC formation;

- glioblastoma stem cells;

- chemical agents against CSCs; t

- ranslational oncology

 

Ira Skvortsova

Guest Editor

 

Invitation to submit your research
cancer_stem-2.pdf
PDF-Dokument [122.0 KB]

 

 

 

21.10.2019

 

Dr. Mariela Vasileva-Slaveva will join the EXTRO-Lab team from November 1, 2019. Mariela has received an ESMO Fellowship-2019 for her project

Breast cancer metastasis and lipid metabolism implication

vasileva-slaveva-mariela

Fellow: Mariela Vasileva-Slaveva
Home institute: Alexandrovska University Hospital, Sofia, Bulgaria
Host institute: Innsbruck Medical University, EXTRO-Lab, Dept. Of Therapeutic Radiology and Oncology (scientific supervisor Ira Skvortsova)

www.esmo.org

ESMO Fellowship Programme Brochure

 

 

 

16.09.2019

 

Dr. Irma Kvitsaridze, Radiation Oncologist (Dept. of Therapeutic Radiology and Oncology) has started her cooperation with the EXTRO-Lab team. Irma will conduct her clinical research projects in cooperation with lab members.

 

August 1, 2019

 

PhD Student Bertram Aschenbrenner has been awarded with the Marietta Blau Grant. Marietta Blau Grant supports the PhD Student's research activities in foreign countries to improve an impact of their PhD thesis: 

https://oead.at/en/outgoing/higher-education/scholarships-for-studying-abroad/marietta-blau-grant/

 

Bertram Aschenbrenner will work for 6 months on the project "Radiation-induced ferroptosis as a tool to combat metastatic breast cancer" at the National Insitute for Quantum and Radiological Science and Technology (QST) in Chiba (Japan). Bertram will perform his study in collaboration with Dr. Ryoichi Hirayama, and the effect of heavy ion radiotherapy (carbon ions) on breast cancer stem cells will be studied.

 

 

July 10-12, 2019

 

EXTRO-Lab has extended its international collaborations. Cancer researchers Prof. Dr. Rusudan Sujashvili and Dr. Mariam Abuladze (New Vision University, Tbilisi, Gergia) have visited the EXTRO-Lab. Both Georgian and Austrian partners will work on the problems of breast cancer treatment.

 

 

 

04.07.2018

 

EXTRO-Lab members participated in the EACR-25 in Amsterdam:

 

Our PhD Students Giulia Negro and Bertram Aschenbrenner presented their recent data on the radioresistance of breast cancer cells. Their Poster presentations were presented at the Poster Session "Radiobiology, Radiation Oncology":

PO-115 Radiation resistance mechanisms of breast cancer cells

G. Negro, B. Aschenbrenner, S. Skvortsov, C. Jimenez, U. Ganswindt, I. Skvortsova
 

PO-120 Metastatic breast cancer: Underlying molecular mechanisms of radiation response

B. Aschenbrenner, G. Negro, S. Skvortsov, U. Ganswindt, S. Kranjc, M. Čemažar, I. Skvortsova.
 

We thank all colleagues contributed to the research projects, and we hope on further fruitful collaboration!

 

See photos from the EACR-25 here: Photos from EACR-25

 

 

01.05.2018

 

EXTRO-Lab has new PhD Student Dragana Savic:

 

Our new colleague PhD Student Dragana Savic will work on the ÖNB project 17620 "Non-invasive exosome-based method to predict HNSCC recurrence after radiotherapy".

 

01.05.2018

 

Laura Pezze is a guest researcher in Innsbruck:

 

Laura Pezze has received an EACR fellowship to perform a part of her research project at EXTRO-Lab. Laura is a PhD Student at CIBIO, Laboratory of Molecular Cancer Genetics, Trento, Italy

 

04.04.2018

 

Life Science PhD Meeting in Innsbruck:

https://www.i-med.ac.at/oeh/phd/lifesciencemeeting18/photos.html

 

PhD Student Bertram Aschenbrenner has presented his recent data at the meeting. His research was supported by the FWF (Austrian Science Fund), Ingrid Shaker-Nesmann Foundation, and WTZ-ÖAD Austrian-Slovenian Project. EXTRO-Lab team specially thanks our Slovenian colleagues Dr. Simona Kranjc and Prof. Dr. Maja Cemazar for the performed in vivo experiments.

 

28.02.2018

 

EACR Conference Series:

https://www.eacr.org/conference-series

 

EACR Ambassador Ira Skvortsova is inviting you to attend the EACR Conferences.

 

28.02.2018

 

Today is the last day to submit your abstract to the EACR-25 (30 June - 3 July 2018, Amsterdam, the Netherlands)

http://www.eacr25.org/abstracts

 

Visit the EACR Website and submit your abstract!

 

26.02.2018

 

PhD Student Giulia Negro has been awarded a travel grant to attend a FEBS Conference "Emerging issues of breast cancer research: tumour heterogeneity, immunotherapy, and cellular metabolism (4-8 April 2018, Budapest, Hungary)

Owing to the financial support from the Austrian Science Fund (FWF Project P29457), Ingrid Shaker Nessmann Cancer Research Foundation, and OeAD (Sl 25/2018), Giulia has received interesting research data underlying the radiation resistance of metastatic breast cancer cells. These results will be presented at the conference in Budapest. Good luck, Giulia!

 

 

02.01.2018

Financial Support from the Austrian National Bank (ÖNB)

Next project by Ira Skvortsova was granted by the ÖNB Foundation:

Non-invasive exosome-based method to predict HNSCC recurrence after radiotherapy

https://www.i-med.ac.at/mypoint/news/715860.html

 

 

 

 

 

Merry Christmas and Happy New 2018 Year!

 

 

 

 

December 7, 2017

 

EXTRO-Lab team has participated in the competition to get a Nanolive 3D-Cell Explorer Microscope to realize a research project, and the results of this competition were announced on December 4, 2017

http://nanolive.ch/the-winner-of-the-3d-cell-explorer-competition-is/

 

 

 

September 26-27, 2017: Invitation

Seminar and Lionheart Instrument Demonstration:

Dr. Fabian Kuck (BioTek) will be presenting the Lionheart FX Live-Cell Imager.

 

In this presentation we will talk about how quantitative image-based results for cell biology can be achieved through automated digital microscopy and image analysis techniques under both fixed and live cell conditions. Lionheart™ FX Automated Microscope is an inclusive microscopy system, optimized for live cell imaging with up to 100x air and oil immersion magnification, with brightfield, color brightfield, phase contrast and fluorescence channels. A unique environment control cover provides incubation to 40°C and effective containment for CO2/O2 control. The available humidity chamber and reagent injection port add a greater level of environment optimization for live cell imaging workflows. Lionheart FX and Gen5 together comprise Augmented Microscopy™ - the automation of image capture, processing, analysis and development of publication-ready images and data.

Please join us for the

Instrument demonstration:

When: Tuesday September 26, 2017 at 13:00

Where: TKFI, Labor 1 (Innrain 66)

Lionheart FX Live-Cell Imager Seminar:

When: Wednesday September 27, 2017 at 10:00

Where: TKFI Seminar room (Innrain 66A, G0)

 

September 2017: Giulia Negro has presented the recent data on breast cancer stem cells at the 12th Annual Meeting of the EORTC PathoBiology Group in Aviano (Italy), September 14-16, 2017.

We will report on the meeting and Giulia's presentation in the EXTRO-Lab Blog. Read us!

 

September 2017: Ira-Ida Skvortsova has been awarded by Immunotools

See here: https://www.extro-lab.at/blog/

 

 

June 2017: Bioscope Summer Course in June 2017, in Caparica (Lisbon, Portugal)

Giulia Negro and Bertram Aschenbrenner will participate in this course:

VII  Hands-on Course in Sample Preparation Using Nanoparticles for Proteomics
 
Module I - Theory
Synthesis and characterization of nanoparticles
Nanoparticle-based sample fractionation
Electrophoresis
Protein identification by Mass Spectrometry
Nano-profiling

 
Module II - Hands-on
Sample clean up
Protein quantification
Nanoparticle synthesis characterization and applications:
Protein fractionation using gold-nanoparticles (serum samples)
Characterization of GNPs-protein complexes (UV-Vis, SDS-PAGE)
In-gel and In-solution protein digestion (GNPs-protein complexes)
Protein identification using MALDI-TOF/TOF MS
Data analysis

http://www.bioscopegroup.org/index.php/activities/courses

 

We are waiting for interesting reports!

 

 

 

 

Seminar and ELLA Instrument Demonstration (180 min.)

Dr. Michael V. Stein (European Business  Manager Immunoassay Solutions Luminex & SimplePlex, Bio-Techne) will be presenting SimplePlex Assay.

Please join us for this presentation.

When: Tuesday May 16, 2017 at 10:00

Where: Tyrolean Cancer Research Institute (TKFI)

 

 

 

 

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